So let me ask this, You said 2 out of 4 disk failed in the unit. So you should have 2 drives that our in the unit and are working to where you can access the unit right? If so leave those drives alone or its going to be hard to get your unit to work again.
You dont need to fdisk the drives. In windows, simply delete the partition in Disk management. This will make it unallocated. Do this to the new drives. NOT the old ones. You need the old ones to get the OS/Boot info on the new disk.
Once the drives have no partition. Put them where the other disk failed. For example if disk 2 and 4 failed you will replace 2 and 4, leave 1 and 3 alone for now if you are going to replace them all.
This unit has what they call quick swap.. guess a early version of hotswap.. didnt look in to it much. So you should be able to replace the drives why the unit is on OR power it off and replace them and power it back up. You will need to format the drives to get the OS/Boot on them. Once there formatted. delete any array you have if you are going to replace all 4 disk and start from scratch. If not then DONT delete the array. Simple rebuild the array if possible. If you were in a RAID 5. you might as well delete the array and start from scratch.