Sounds like a similar issue i had with the TS5200. I updated to the new firmware they just release and that fix my issue was transferring about 200GB image of a server and keep freezing. Here are the release notes to the new firmware. If anything i would try getting the new firmware and see if that helps.
[Firmware Release Note]
Version 2.42 [2013.9.12]
=Added and modified features
[RAID]
- Added the option to cancel the resync after creating a RAID array.
=Bug fixes
- Fixed the bug where the backup or replication target TeraStation freezes when hundreds gigabyte of files are backed up using backup or replication.
- Fixed the bug where the TeraStation freezes when hundreds gigabyte of files are copied via samba.
- Fixed the bug where Settings is not accessible after initializing the admin password using a password recovery USB drive.
- Fixed the bug where some files are not restored after using a USB drive to restore settings.
- Fixed the bug where the TeraStation cannot be accessed after a USB drive format failure.
[RAID]
- Fixed the bug where RAID scanning doesn't work on the first day of each month.
[Samba]
- Fixed the bug where files become read-only to everyone other than the file owner when creating or editing a shared folder from Settings while the shared folder is open.
[Replication and failover]
- Fixed the bug where files containing single quotations in their filename cannot be copied to replication or failover targets.
- Fixed the bug where some files cannot be copied to their replication target when the TeraStation is rebooted after an abnormal shutdown.
- Fixed the bug where replication tasks don't work when the replication target USB drive is disconnected.
[DLNA]
- Fixed the bug where the TeraStation's icon isn't displayed by DLNA client devices.
[Settings]
- Fixed the bug where the "Random Generation" button for BuffaloNAS.com keys didn't work properly.
- Fixed the bug where group quota settings weren't displayed properly.
- Now WebAccess remote and Amazon S3 may be used at the same time.
(I decided to provide the link just in case some people don't know how to find it)
Firmware Download Link:
http://www.buffalotech.com/support-and-downloads/download/ts5000-242en.zip