I am having the same problem. I put in a new wireless router and I now I get the I53 amber led error. My cloudstor doesn't work on Pogoplug.com anymore. I've tried resetting, made sure UPnP is enabled on the router and it still doesn't work. I even tried swapping back to my old router, but it's stuck with the problem now and I can't get it to work. I can connect to the drive no problem when I'm on the local network, but no cloud access now.
Anyone have any ideas or how to fix this? It's the whole point of a "cloud" drive!