I just spent HOURS trying to get mine to work -- same problem! I'm on Windows 7, though. Same with USB plugging, unplugging. I have had one problem after another since I got this hard drive in spite of the rave reviews (the reason I bought it). But this beats all. There's no work-around because it isn't recognized by Windows.
I have done all this today:
Rebooted
restored Windows to how it was before today's update & rebooted (both with the drive unplugged and then plugged back in after reboot and leaving plugged in)
changed USB ports (front of machine to back for different bus)
did rebooting after changing ports
uninstalled last update (4/24) before today's, which is the last time I used the hard drive (and it worked then)
rebooted again, drive unplugged
tried to update firmware, but it won't because it says the drive isn't connected
windows says drivers are up to date
Might be more. Some of the steps have been repeated. I also spent over an hour on the phone with my brother, who is the IT guy with a large corporation. He lives too far to come over, otherwise he would have opened up the drive and tried to find another way to connect it for me.
I hope someone has a solution to this quickly. It doesn't help to have a backup drive you can't access!
Thanks in advance.